The JAK/STAT pathway regulates proximo-distal patterning inDrosophila
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چکیده
منابع مشابه
Diffusible signals and epigenetic timing cooperate in late proximo-distal limb patterning.
Developing vertebrate limbs initiate proximo-distal patterning by interpreting opposing gradients of diffusible signaling molecules. We report two thresholds of proximo-distal signals in the limb bud: a higher threshold that establishes the upper-arm to forearm transition; and a lower one that positions a later transition from forearm to hand. For this last transition to happen, however, the si...
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Learning constraints and guiding mechanisms are involved since the very beginning of the infant development. Allowing a progressive and open-ended scaffolding of new skills, these mechanisms have been described as crucial, by psychologists and neuroscientists. Developmental heuristics presented here are directly inspired by the ability to control the growth of complexity of both exploration and...
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The appendages of insects and vertebrates develop as extensions of the body wall. During development, a proximo-distal axis for growth and patterning is created in each appendage, in order to specify appendage length and allocation of pattern elements like joints and sensory organs. Here we use the expression of molecular markers to examine how PD development takes place in the legs of the frui...
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Lung development is a highly regulated process directed by mesenchymal-epithelial interactions, which coordinate the temporal and spatial expression of multiple regulatory factors required for proper lung formation. The Iroquois homeobox (Irx) genes have been implicated in the patterning and specification of several Drosophila and vertebrate organs, including the heart. Herein, we investigated ...
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IT IS known that enzyme distribution is not the same among various fibre tracts, but except for LUBLINSKA’S (1 962) report of a proximo-distal decrease of cholinesterase along peripheral nerves there is little information about differences of enzyme activity along the course of a given fibre tract. This paper presents biochemical and histochemical data of the distribution of lactate dehydrogena...
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ژورنال
عنوان ژورنال: Developmental Dynamics
سال: 2007
ISSN: 1058-8388,1097-0177
DOI: 10.1002/dvdy.21348